ID   PhB1
AC   CVCL_D6FU
DR   Wikidata; Q127383063
RX   PubMed=8140859;
RX   PubMed=10071072;
RX   PubMed=10576511;
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=8140859; PubMed=10071072; PubMed=10576511).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   56Y
CA   Transformed cell line
DT   Created: 02-05-24; Last updated: 19-12-24; Version: 3
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RX   PubMed=8140859; DOI=10.1159/000204456;
RA   Knuutila S., Lindlof M., Kovanen P.E., Ramqvist T., Ruutu T.,
RA   Andersson L.C.;
RT   "Philadelphia chromosome as the sole abnormality and p210 bcr-abl
RT   chimeric protein expression in an Epstein-Barr virus-transformed B
RT   cell line from a patient with chronic myeloid leukemia.";
RL   Acta Haematol. 90:190-194(1993).
//
RX   PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4;
RA   Drexler H.G., MacLeod R.A.F., Uphoff C.C.;
RT   "Leukemia cell lines: in vitro models for the study of Philadelphia
RT   chromosome-positive leukemia.";
RL   Leuk. Res. 23:207-215(1999).
//
RX   PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9;
RA   Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.;
RT   "ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";
RL   Leuk. Res. 23:1055-1060(1999).
//