Cellosaurus cell line HyCyte OCI-AML3 KO-hFGL2 (CVCL

Cross-references
Cell line name	HyCyte OCI-AML3 KO-hFGL2
Synonyms	hFGL2 knockout OCI-AML3
Accession	CVCL_D6C9
Resource Identification Initiative	To cite this cell line use: HyCyte OCI-AML3 KO-hFGL2 (RRID:CVCL_D6C9)
Comments	Population: Caucasian. Doubling time: 24-36 hours (Hysigen=CGKO-M2505). Knockout cell: Method=CRISPR/Cas9; HGNC; 3696; FGL2. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; 2978; DNMT3A; Simple; p.Arg882Cys (c.2644C>T); ClinVar=VCV000375882; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 7910; NPM1; Simple; p.Trp288Cysfs*12 (c.860_863dupTCTG); ClinVar=VCV000013998; Zygosity=Heterozygous (from parent cell line).
Disease	Adult acute myeloid leukemia (NCIt: C9154) Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1844 (OCI-AML-3)
Sex of cell	Male
Age at sampling	57Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M2505
Encyclopedic resources	Wikidata; Q127382046
Entry history
Entry creation	02-May-2024
Last entry update	10-Sep-2024
Version number	2