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Cellosaurus HyCyte MCF-7 KO-hINSR (CVCL_D6C4)

[Text version]
Cell line name HyCyte MCF-7 KO-hINSR
Synonyms hINSR knockout MCF-7
Accession CVCL_D6C4
Resource Identification Initiative To cite this cell line use: HyCyte MCF-7 KO-hINSR (RRID:CVCL_D6C4)
Comments Population: Caucasian.
Doubling time: 48-72 hours (Hysigen=CGKO-M2533).
Knockout cell: Method=CRISPR/Cas9; HGNC; 6091; INSR.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2533
Encyclopedic resources Wikidata; Q127382041
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2