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Cellosaurus HyCyte BXPC-3 KO-hITGB6 (CVCL_D6AY)

[Text version]
Cell line name HyCyte BXPC-3 KO-hITGB6
Synonyms hITGB6 knockout BXPC-3
Accession CVCL_D6AY
Resource Identification Initiative To cite this cell line use: HyCyte BXPC-3 KO-hITGB6 (RRID:CVCL_D6AY)
Comments Population: Caucasian.
Doubling time: 48-60 hours (Hysigen=CGKO-M2458).
Knockout cell: Method=CRISPR/Cas9; HGNC; 6161; ITGB6.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; None_reported; -; Zygosity=- (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0186 (BxPC-3)
Sex of cell Female
Age at sampling 61Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2458
Entry history
Entry creation02-May-2024
Last entry update02-May-2024
Version number1