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Cellosaurus HyCyte A-549 KO-hMUC4 (CVCL_D6AN)

[Text version]
Cell line name HyCyte A-549 KO-hMUC4
Synonyms hMUC4 knockout A-549
Accession CVCL_D6AN
Resource Identification Initiative To cite this cell line use: HyCyte A-549 KO-hMUC4 (RRID:CVCL_D6AN)
Comments Population: Caucasian.
Doubling time: 48-72 hours (Hysigen=CGKO-M2527).
Knockout cell: Method=CRISPR/Cas9; HGNC; 7514; MUC4.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2527
Encyclopedic resources Wikidata; Q127381988
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2