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Cellosaurus HyCyte 22RV1 KO-hFOXA1 (CVCL_D6A1)

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Cell line name HyCyte 22RV1 KO-hFOXA1
Synonyms hFOXA1 knockout 22RV1
Accession CVCL_D6A1
Resource Identification Initiative To cite this cell line use: HyCyte 22RV1 KO-hFOXA1 (RRID:CVCL_D6A1)
Comments Population: Caucasian.
Doubling time: 24-48 hours (Hysigen=CGKO-M2386).
Knockout cell: Method=CRISPR/Cas9; HGNC; 5021; FOXA1.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Leu597Arg (c.1790T>G); ClinVar=VCV000013968; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7133; KMT2D; Simple; p.Arg1252Ter (c.3754C>T); ClinVar=VCV000167228; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7133; KMT2D; Simple; p.Gln3158Ter (c.9472C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Gln546Arg (c.1637A>G); ClinVar=VCV000045466; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln331Arg (c.992A>G); ClinVar=VCV000421319; Zygosity=Heterozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1045 (22Rv1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2386
Encyclopedic resources Wikidata; Q127381965
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2