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Cellosaurus P388/CPT45 (CVCL_D638)

[Text version]
Cell line name P388/CPT45
Synonyms P388CPT45; P388/CPT; CPT45
Accession CVCL_D638
Resource Identification Initiative To cite this cell line use: P388/CPT45 (RRID:CVCL_D638)
Comments Selected for resistance to: ChEBI; CHEBI:27656; Camptothecin (CPT).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_D640 (P388/S)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=2172765
Eng W.K., McCabe F.L., Tan K.B., Mattern M.R., Hofmann G.A., Woessner R.D., Hertzberg R.P., Johnson R.K.
Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content.
Mol. Pharmacol. 38:471-480(1990)

PubMed=14679002
Li T.-K., Houghton P.J., Desai S.D., Daroui P., Liu A.A., Hars E.S., Ruchelman A.L., LaVoie E.J., Liu L.F.
Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug.
Cancer Res. 63:8400-8407(2003)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3307567
ChEMBL-Targets; CHEMBL614223
PubChem_Cell_line; CVCL_D638
Encyclopedic resources Wikidata; Q54937264
Entry history
Entry creation22-Oct-2012
Last entry update21-Mar-2023
Version number13