ID   mtop2beta-6
AC   CVCL_D634
DR   Wikidata; Q54907015
RX   PubMed=10570059;
CC   Knockout cell: Method=Homologous recombination; MGI; MGI:98791; Top2b.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Embryo
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 9
//
RX   PubMed=10570059; DOI=10.1124/mol.56.6.1309;
RA   Errington F., Willmore E., Tilby M.J., Li L., Li G., Li W.,
RA   Baguley B.C., Austin C.A.;
RT   "Murine transgenic cells lacking DNA topoisomerase IIbeta are
RT   resistant to acridines and mitoxantrone: analysis of cytotoxicity and
RT   cleavable complex formation.";
RL   Mol. Pharmacol. 56:1309-1316(1999).
//