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Cellosaurus A2780/CBP (CVCL_D620)

[Text version]
Cell line name A2780/CBP
Synonyms A-car
Accession CVCL_D620
Resource Identification Initiative To cite this cell line use: A2780/CBP (RRID:CVCL_D620)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI_31355; Carboplatin (CBP; Paraplatin).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=15254775; DOI=10.3892/ijmm.14.2.257
Li L., Luan Y.-Z., Wang G.-D., Tang B.-J., Li D.-R., Zhang W., Li X.-P., Zhao J.-S., Ding H., Reed E., Li Q.-D.Q.
Development and characterization of five cell models for chemoresistance studies of human ovarian carcinoma.
Int. J. Mol. Med. 14:257-264(2004)

PubMed=17269733; DOI=10.1021/pr060402r
Yan X.-D., Pan L.-Y., Yuan Y., Lang J.-H., Mao N.
Identification of platinum-resistance associated proteins through proteomic analysis of human ovarian cancer cells and their platinum-resistant sublines.
J. Proteome Res. 6:772-780(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D620
Encyclopedic resources Wikidata; Q54606598
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number16