ID   KB-C2
AC   CVCL_D600
SY   KBC2
DR   BTO; BTO:0005215
DR   Wikidata; Q54899550
RX   PubMed=3711108;
RX   PubMed=3857583;
RX   PubMed=11509122;
CC   Problematic cell line: Contaminated. Ancestral cell line (KB) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:23359; Colchicine.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1D80 ! KB-C1.5
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 16
//
RX   PubMed=3711108; DOI=10.1016/S0021-9258(19)57466-X;
RA   Shen D.-W., Cardarelli C., Hwang J., Cornwell M., Richert N., Ishii S.,
RA   Pastan I., Gottesman M.M.;
RT   "Multiple drug-resistant human KB carcinoma cells independently
RT   selected for high-level resistance to colchicine, adriamycin, or
RT   vinblastine show changes in expression of specific proteins.";
RL   J. Biol. Chem. 261:7762-7770(1986).
//
RX   PubMed=3857583; DOI=10.1073/pnas.82.8.2330;
RA   Richert N., Akiyama S.-i., Shen D.-W., Gottesman M.M., Pastan I.;
RT   "Multiply drug-resistant human KB carcinoma cells have decreased
RT   amounts of a 75-kDa and a 72-kDa glycoprotein.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:2330-2333(1985).
//
RX   PubMed=11509122; DOI=10.1111/j.1349-7006.2001.tb01177.x;
RA   Aoki S., Chen Z.-S., Higasiyama K., Setiawan A., Akiyama S.-i.,
RA   Kobayashi M.;
RT   "Reversing effect of agosterol A, a spongean sterol acetate, on
RT   multidrug resistance in human carcinoma cells.";
RL   Jpn. J. Cancer Res. 92:886-895(2001).
//