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Cellosaurus PC3-STEAP-1 (CVCL_D5ZS)

[Text version]
Cell line name PC3-STEAP-1
Accession CVCL_D5ZS
Resource Identification Initiative To cite this cell line use: PC3-STEAP-1 (RRID:CVCL_D5ZS)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11378; STEAP1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=17575147; DOI=10.1158/0008-5472.CAN-06-3849
Challita-Eid P.M., Morrison K., Etessami S., An Z.-L., Morrison K.J.M., Perez-Villar J.J., Raitano A.B., Jia X.-C., Gudas J.M., Kanner S.B., Jakobovits A.
Monoclonal antibodies to six-transmembrane epithelial antigen of the prostate-1 inhibit intercellular communication in vitro and growth of human tumor xenografts in vivo.
Cancer Res. 67:5798-5805(2007)

Cross-references
Encyclopedic resources Wikidata; Q127383024
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3