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Cellosaurus CEC-32/chMx-Luc (CVCL_D5YC)

[Text version]
Cell line name CEC-32/chMx-Luc
Accession CVCL_D5YC
Resource Identification Initiative To cite this cell line use: CEC-32/chMx-Luc (RRID:CVCL_D5YC)
Comments Group: Bird cell line.
Problematic cell line: Misidentified. Parent cell line (CEC-32) was originally thought to be of chicken origin but found to be from quail.
Characteristics: Used in a bioassay for the sensitive detection of chicken IFN (ChIFN) (PubMed=15035851).
Characteristics: Expresses luciferase under the control of the IFN-inducible chicken gene Mx promoter (PubMed=7518167).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) (NCBI Taxonomy: 93934)
Hierarchy Parent: CVCL_D160 (CEC-32)
Category Spontaneously immortalized cell line
Publications

PubMed=7518167; DOI=10.1006/viro.1994.1464
Schumacher B., Bernasconi D., Schultz U., Staeheli P.
The chicken Mx promoter contains an ISRE motif and confers interferon inducibility to a reporter gene in chick and monkey cells.
Virology 203:144-148(1994)

PubMed=15035851; DOI=10.1089/107999004322917025
Schwarz H., Harlin O., Ohnemus A., Kaspers B., Staeheli P.
Synthesis of IFN-beta by virus-infected chicken embryo cells demonstrated with specific antisera and a new bioassay.
J. Interferon Cytokine Res. 24:179-184(2004)

Cross-references
Encyclopedic resources Wikidata; Q127380429
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2