ID   MCF-7 1403
AC   CVCL_D5YB
DR   Wikidata; Q127382747
RX   DOI=10.1016/S0531-5131(03)01154-3;
CC   Population: Caucasian.
CC   Characteristics: Transfected with a firefly luciferase reporter gene under the control of the clusterin promoter (DOI=10.1016/S0531-5131(03)01154-3).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D5YA ! MCF-7:WS8
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 10-09-24; Version: 2
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RX   DOI=10.1016/S0531-5131(03)01154-3;
RA   Klokov D., Criswell T.L., Sampath L., Leskov K.S., Frinkley K., Araki S.,
RA   Beman M., Wilson D.L., Boothman D.A.;
RT   "Clusterin: a protein with multiple functions as a potential ionizing
RT   radiation exposure marker.";
RL   Int. Congr. Ser. 1258:219-232(2003).
//