ID   LT97-2
AC   CVCL_D5XV
DR   Wikidata; Q127382707
RX   DOI=10.25365/thesis.6275;
CC   Characteristics: Are 10-70% CD44+ (DOI=10.25365/thesis.6275).
CC   Doubling time: 72-96 hours (DOI=10.25365/thesis.6275).
CC   Sequence variation: Gene deletion; HGNC; HGNC:583; APC; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu257Arg (c.770T>G); ClinVar=VCV000142134; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.1100+30A>T; ClinVar=VCV000810938; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C5673; Colorectal adenoma
DI   NCIt; C3339; Familial adenomatous polyposis
DI   ORDO; Orphanet_733; Familial adenomatous polyposis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A9BJ ! LT97
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 19-12-24; Version: 3
//
RX   DOI=10.25365/thesis.6275;
RA   Koneczny I.;
RT   "Investigating a model cell line for tumour stem cells in colorectal
RT   cancer.";
RL   Thesis MSc (2009); University of Vienna; Vienna; Austria.
//