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Cellosaurus PPMI.I.1097.1 (CVCL_D5TP)

[Text version]
Cell line name PPMI.I.1097.1
Synonyms PPMI51782
Accession CVCL_D5TP
Resource Identification Initiative To cite this cell line use: PPMI.I.1097.1 (RRID:CVCL_D5TP)
Comments Part of: Parkinson's Progression Markers Initiative (PPMI) cell line panel.
Population: Caucasian, not Hispanic.
Donor information: At sampling established from a patient at the prodromal stage of Parkinson disease.
Miscellaneous: PPMI study cohort prodromal, PPMI study subgroup LRRK2.
Caution: The PPMI51782 identifier corresponds to an internal donor ID at PPMI. As multiple iPSC clones have been established from the cells of this donor, this identifier should not be cited in a publication.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Parkinson disease 8, autosomal dominant (NCIt: C198605)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D5TQ ! PPMI.I.1097.2
CVCL_D5TR ! PPMI.I.1097.3
Sex of cell Female
Age at sampling 69Y
Category Induced pluripotent stem cell
Web pages https://www.ppmi-info.org/access-data-specimens/download-data
https://www.michaeljfox.org/sites/default/files/media/document/2018%20-%20PDTC%20-%20NKP%20Poster%20on%20iPSCs.pdf
Publications

PubMed=34434090; DOI=10.3389/fnmol.2021.734273; PMCID=PMC8381147
Nguyen D., Bharat V., Conradson D.M., Nandakishore P., Wang X.-N.
Miro1 impairment in a Parkinson's at-risk cohort.
Front. Mol. Neurosci. 14:734273.1-734273.8(2021)

PubMed=35895835; DOI=10.1126/scitranslmed.abp8869; PMCID=PMC9809150
Langston R.G., Beilina A., Reed X., Kaganovich A., Singleton A.B., Blauwendraat C., Gibbs J.R., Cookson M.R.
Association of a common genetic variant with Parkinson's disease is mediated by microglia.
Sci. Transl. Med. 14:eabp8869.1-eabp8869.12(2022)

Cross-references
Encyclopedic resources Wikidata; Q127383518
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3