ID   TMD12
AC   CVCL_D5KS
SY   Tokyo Medical and Dental university 12
DR   Wikidata; Q127384397
RX   PubMed=36191884;
CC   Population: Japanese.
CC   Doubling time: ~24 hours (PubMed=36191884).
CC   Sequence variation: Mutation; HGNC; HGNC:1699; CD79B; Simple; p.Tyr196Asn (c.586T>A); Zygosity=Heterozygous (PubMed=36191884).
CC   Sequence variation: Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Leu265Pro (c.794T>C); Zygosity=Heterozygous (PubMed=36191884).
CC   Sequence variation: Mutation; HGNC; HGNC:8986; PIM1; Simple; c.880+1G>A; Zygosity=Heterozygous; Note=Splice donor mutation (PubMed=36191884).
CC   Sequence variation: Mutation; HGNC; HGNC:12825; XPO1; Simple; p.Glu571Lys (c.1711G>A); ClinVar=VCV000376695; Zygosity=Heterozygous (PubMed=36191884).
CC   Omics: Deep exome analysis.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C36081; Diffuse large B-cell lymphoma activated B-cell type
DI   ORDO; Orphanet_544; Diffuse large B-cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 19-12-24; Version: 3
//
RX   PubMed=36191884; DOI=10.1016/j.exphem.2022.09.005;
RA   Nagao T., Yoshifuji K., Sadato D., Motomura Y., Saito M., Yamamoto K.,
RA   Yamamoto K., Nogami A.;
RT   "Establishment and characterization of a new activated B-cell-like
RT   DLBCL cell line, TMD12.";
RL   Exp. Hematol. 116:37-49(2022).
//