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Cellosaurus U266B1-Fluc-EmGFP (CVCL_D5KP)

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Cell line name U266B1-Fluc-EmGFP
Accession CVCL_D5KP
Resource Identification Initiative To cite this cell line use: U266B1-Fluc-EmGFP (RRID:CVCL_D5KP)
Comments Population: Caucasian.
Characteristics: Reporter cell line, transfected with the LV-SFFV-Luc2-P2A-EmGFP vector encoding for luciferase linked via a P2A cleavage site to emerald green fluorescent protein (emGFP) and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL176).
Characteristics: Produces IgE lambda (from parent cell line).
Transfected with: UniProtKB; P42212; GFP (with p.Ser65Thr, p.Ser72Ala, p.Asn149Lys, p.Met153Thr, p.Ile167Thr and p.His231Leu = EmGFP).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0566 (U266B1)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Imanis; CL176
Entry history
Entry creation02-May-2024
Last entry update02-May-2024
Version number1