ID   HeLa Flp-In T-REx PINK1 KO clone 3C9
AC   CVCL_D5JI
SY   Flp-In T-Rex HeLa PINK1 CRISPR/Cas9 knock-out
DR   Wikidata; Q127381684
RX   PubMed=35042401;
CC   Population: African American.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 14581; PINK1.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C4ET ! HeLa Flp-In T-REx
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 10-09-24; Version: 2
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RX   PubMed=35042401; DOI=10.1098/rsob.210264; PMCID=PMC8767193;
RA   Kakade P.S., Ojha H., Raimi O.G., Shaw A., Waddell A.D., Ault J.R.,
RA   Burel S., Brockmann K., Kumar A., Ahangar M.S., Krysztofinska E.M.,
RA   Macartney T., Bayliss R., Fitzgerald J.C., Muqit M.M.K.;
RT   "Mapping of a N-terminal alpha-helix domain required for human PINK1
RT   stabilization, serine228 autophosphorylation and activation in
RT   cells.";
RL   Open Biol. 12:210264.1-210264.16(2022).
//