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Cellosaurus MDCK-dEGF/HBEGF/TGFalpha/EREG KO 2 (CVCL_D5I4)

[Text version]
Cell line name MDCK-dEGF/HBEGF/TGFalpha/EREG KO 2
Synonyms MDCK-QKO
Accession CVCL_D5I4
Resource Identification Initiative To cite this cell line use: MDCK-dEGF/HBEGF/TGFalpha/EREG KO 2 (RRID:CVCL_D5I4)
Comments Knockout cell: Method=CRISPR/Cas9; VGNC; 40235; EGF.
Knockout cell: Method=CRISPR/Cas9; VGNC; 111490; EREG.
Knockout cell: Method=CRISPR/Cas9; VGNC; 41609; HBEGF.
Knockout cell: Method=CRISPR/Cas9; VGNC; 112755; TGFA.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
Hierarchy Parent: CVCL_D5I3 (MDCK-dEGF/HBEGF/TGFalpha KO)
Children:
CVCL_D5IX (MDCK-QKO-EKARrEV-NLS)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=34667080; DOI=10.26508/lsa.202101206; PMCID=PMC8548211
Lin S.-H., Hirayama D., Maryu G., Matsuda K., Hino N., Deguchi E., Aoki K., Iwamoto R., Terai K., Matsuda M.
Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration.
Life Sci. Alliance 5:e202101206.1-e202101206.13(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1970
Encyclopedic resources Wikidata; Q127382774
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2