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Cellosaurus MDCK-dEGF/HBEGF KO (CVCL_D5I2)

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Cell line name MDCK-dEGF/HBEGF KO
Synonyms MDCK-DKO
Accession CVCL_D5I2
Resource Identification Initiative To cite this cell line use: MDCK-dEGF/HBEGF KO (RRID:CVCL_D5I2)
Comments Knockout cell: Method=CRISPR/Cas9; VGNC; 40235; EGF.
Knockout cell: Method=CRISPR/Cas9; VGNC; 41609; HBEGF.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
Hierarchy Parent: CVCL_D5I0 (MDCK-dHBEGF)
Children:
CVCL_D5I3 (MDCK-dEGF/HBEGF/TGFalpha KO)CVCL_D5IT (MDCK-DKO-EKARrEV-NLS)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=34667080; DOI=10.26508/lsa.202101206; PMCID=PMC8548211
Lin S.-H., Hirayama D., Maryu G., Matsuda K., Hino N., Deguchi E., Aoki K., Iwamoto R., Terai K., Matsuda M.
Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration.
Life Sci. Alliance 5:e202101206.1-e202101206.13(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1967
Encyclopedic resources Wikidata; Q127382771
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2