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Cellosaurus SVG-10B1 (CVCL_D5B6)

[Text version]
Cell line name SVG-10B1
Synonyms 10B1
Accession CVCL_D5B6
Resource Identification Initiative To cite this cell line use: SVG-10B1 (RRID:CVCL_D5B6)
Comments Virology: Highly permissive for JC virus (JCV) DNA replication and gene expression and supported persistent and stable JCV infection over months in culture (PubMed=24052414).
Caution: In contrast to SVG p12 (Cellosaurus=CVCL_3797), this cell line is not contaminated with BK polyomavirus (PubMed=25288626).
Derived from site: In situ; Fetal brain; UBERON=UBERON_0006237.
Cell type: Astrocyte; CL=CL_0000127.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5G14 (SVG)
Sex of cell Male
Age at sampling 8-12FW
Category Transformed cell line
Publications

PubMed=24052414; DOI=10.1007/s11481-013-9499-8
Ferenczy M.W., Johnson K.R., Steinberg S.M., Marshall L.J., Monaco-Kushner M.C.G., Beschloss A.M., Jensen P.N., Major E.O.
Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression.
J. Neuroimmun. Pharmacol. 8:1303-1319(2013)

PubMed=25288626; DOI=10.1128/JVI.01600-14
Ferenczy M.W., Major E.O.
Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American Type Culture Collection.
J. Virol. 88:12928-12929(2014)

Entry history
Entry creation02-May-2024
Last entry update02-May-2024
Version number1