ID   HeLa S3 RUBCN KO/HA-Parkin/HaloTag7-mGFP
AC   CVCL_D5AJ
SY   Rubicon KO S3 HeLa + HA-Parkin/pSu9 + HaloTag7-mGFP
DR   Wikidata; Q127381694
RX   DOI=10.1101/2023.08.28.555228;
CC   Population: African American.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 28991; RUBCN.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 8607; PRKN (Note=With a N-terminal HA tag).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P0A3G2; Rhodococcus rhodochrous dhaA (Note=Mutated = HaloTag).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D5AG ! HeLa S3 RUBCN KO clone 15
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 10-09-24; Version: 2
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RX   DOI=10.1101/2023.08.28.555228;
RA   Tudorica D.A., Basak B., Cordova A.P., Khuu G., Rose K., Lazarou M.,
RA   Holzbaur E.L.F., Hurley J.H.;
RT   "A RAB7A phosphoswitch coordinates rubicon homology protein regulation
RT   of PINK1/parkin dependent mitophagy.";
RL   bioRxiv 2023:08.28.555228-08.28.555228(2023).
//