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Cellosaurus CAG (CVCL_D569)

[Text version]
Cell line name CAG
Accession CVCL_D569
Resource Identification Initiative To cite this cell line use: CAG (RRID:CVCL_D569)
Comments Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; 5722; IGKJ4 + HGNC; 5732; IGKV1-16; Name(s)=IGKV1-16-IGKJ4 (CelloPub=CLPUB00604).
  • Gene fusion; HGNC; 5723; IGKJ5 + HGNC; 5732; IGKV1-16; Name(s)=IGKV1-16-IGKJ5 (CelloPub=CLPUB00604).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_XD83 ! ARD
CVCL_D523 ! ARP-1
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Technion Genomics Center

Markers:
AmelogeninX
CSF1PO11,12
D1S165612,14
D2S4419,13
D2S133820
D3S135815,18
D5S81812,13
D7S82010,12
D8S117910,13
D10S124814
D12S39118.3,22
D13S3179
D16S53911,12
D18S5114,15
D19S43313,14
D21S1128,31.2
D22S104515
FGA19,24
Penta D13
Penta E7,15
TH016,7
TPOX11,12
vWA14,18

Run an STR similarity search on this cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
Publications

PubMed=11001907; DOI=10.1182/blood.V96.7.2528
Borset M., Hjertner O., Yaccoby S., Epstein J., Sanderson R.D.
Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins.
Blood 96:2528-2536(2000)

CLPUB00604
Chow S.
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017); University of Toronto; Toronto; Canada

Cross-references
Anatomy/cell type resources BTO; BTO:0005277
Encyclopedic resources Wikidata; Q54808368
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number11