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Cellosaurus OM10.1 (CVCL_D567)

[Text version]
Cell line name OM10.1
Synonyms OM-10.1
Accession CVCL_D567
Resource Identification Initiative To cite this cell line use: OM10.1 (RRID:CVCL_D567)
Comments Population: Caucasian.
Virology: In vitro infected by HIV-1.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Publications

PubMed=1678437; DOI=10.1128/JVI.65.9.4645-4653.1991; PMCID=PMC248919
Butera S.T., Perez V.L., Wu B.-Y., Nabel G.J., Folks T.M.
Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4+ cell model of chronic infection.
J. Virol. 65:4645-4653(1991)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-1319
Cell line databases/resources cancercelllines; CVCL_D567
Encyclopedic resources Wikidata; Q54932007
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number23