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Cellosaurus AT22IJE-T (CVCL_D566)

[Text version]
Cell line name AT22IJE-T
Accession CVCL_D566
Resource Identification Initiative To cite this cell line use: AT22IJE-T (RRID:CVCL_D566)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Leu762Valfs*2 (c.2282_2283CT[1]) (c.2284_2285delCT); ClinVar=VCV000141325; Zygosity=Unspecified (PubMed=9244351).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_F635 (AT22IJE-T pEBS7)CVCL_XG29 (AT22IJE-T pEBS7-YZ3)CVCL_F636 (AT22IJE-T pEBS7-YZ5)
Sex of cell Female
Age at sampling 5Y
Category Transformed cell line
Publications

PubMed=2539904
Ziv Y., Jaspers N.G.J., Etkin S., Danieli T., Trakhtenbrot L., Amiel A., Ravia Y., Shiloh Y.
Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line.
Cancer Res. 49:2495-2501(1989)

PubMed=9244351; DOI=10.1038/sj.onc.1201319
Ziv Y., Bar-Shira A., Pecker I., Russell P., Jorgensen T.J., Tsarfaty I., Shiloh Y.
Recombinant ATM protein complements the cellular A-T phenotype.
Oncogene 15:159-167(1997)

PubMed=9357546; DOI=10.1016/S0027-5107(97)00119-x
Sprung C.N., Bryan T.M., Reddel R.R., Murnane J.P.
Normal telomere maintenance in immortal ataxia telangiectasia cell lines.
Mutat. Res. 379:177-184(1997)

Cross-references
Encyclopedic resources Wikidata; Q54750854
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number14