ID   HEK293-NOD2
AC   CVCL_D4ZL
SY   FLP-IN HEK 293-NOD2wt
DR   GEO; GSM560855
DR   GEO; GSM560856
DR   GEO; GSM560857
DR   GEO; GSM560864
DR   GEO; GSM560865
DR   GEO; GSM560866
DR   GEO; GSM560873
DR   GEO; GSM560874
DR   GEO; GSM560875
DR   Wikidata; Q127381645
RX   PubMed=16257953;
RX   PubMed=21335489;
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 5331; NOD2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_U427 ! Flp-In-T-REx-293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 02-05-24; Last updated: 10-09-24; Version: 2
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RX   PubMed=16257953; DOI=10.1074/jbc.M505986200;
RA   Weichart D., Gobom J., Klopfleisch S., Hasler R., Gustavsson N.,
RA   Billmann-Born S., Lehrach H., Seegert D., Schreiber S., Rosenstiel P.;
RT   "Analysis of NOD2-mediated proteome response to muramyl dipeptide in
RT   HEK293 cells.";
RL   J. Biol. Chem. 281:2380-2389(2006).
//
RX   PubMed=21335489; DOI=10.4049/jimmunol.1000085;
RA   Billmann-Born S., Till A., Arlt A., Lipinski S., Sina C., Latiano A.,
RA   Annese V., Hasler R., Kerick M., Manke T., Seegert D., Hanidu A.,
RA   Schafer H., van Heel D., Li J., Schreiber S., Rosenstiel P.;
RT   "Genome-wide expression profiling identifies an impairment of negative
RT   feedback signals in the Crohn's disease-associated NOD2 variant
RT   L1007fsinsC.";
RL   J. Immunol. 186:4027-4038(2011).
//