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Cellosaurus CW1474 (CVCL_D4Z7)

[Text version]
Cell line name CW1474
Accession CVCL_D4Z7
Resource Identification Initiative To cite this cell line use: CW1474 (RRID:CVCL_D4Z7)
Comments Population: Caucasian.
Characteristics: Established from a patient-derived xenograft (PubMed=35934060).
Doubling time: 41 hours (Direct_author_submission).
Omics: Deep exome analysis.
Miscellaneous: Doubling time, TP53 mutation, age at sampling and ethnic origin of patient from personal communication of Blum, Andrew E.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly279_Thr284del; Zygosity=Homozygous (Direct_author_submission).
Disease Esophageal adenocarcinoma (NCIt: C4025)
Adenocarcinoma of the esophagus (ORDO: Orphanet_99976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 86Y
Category Cancer cell line
Publications

PubMed=35934060; DOI=10.1053/j.gastro.2022.07.073; PMCID=PMC9613531
Blum A.E., Ravillah D., Katabathula R.M., Khalighi S., Varadan V., Guda K.
Betrnet Consortium
HNF4A defines molecular subtypes and vulnerability to transforming growth factor beta-pathway targeted therapies in cancers of the distal esophagus.
Gastroenterology 163:1457-1460(2022)

PubMed=37182784; DOI=10.1053/j.gastro.2023.04.037; PMCID=PMC10524377
Ravillah D., Kieber-Emmons A.L., Singh S., Keerthy K.S., Blum A.E., Guda K.
Betrnet Consortium
Discovery and initial characterization of long intergenic noncoding RNAs associated with esophageal adenocarcinoma.
Gastroenterology 165:505-508.e7(2023)

Cross-references
Cell line collections (Providers) ATCC; CRL-3529
Encyclopedic resources Wikidata; Q127380727
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3