ID   Calu6 Krev-4
AC   CVCL_D4Y4
DR   Wikidata; Q127380398
RX   PubMed=1485916;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61Lys (c.180_181TC>CA) (c.180_181delinsCA); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:9855; RAP1A.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: Epithelial cell; CL=CL_0000066.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0236 ! Calu-6
SX   Female
AG   61Y
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 14-08-25; Version: 4
//
RX   PubMed=1485916; DOI=10.1002/mc.2940060406;
RA   Caamano, Jorge H.
RA   DiRado, Marion
RA   Iizasa, Toshihiko
RA   Momiki, Shigeru
RA   Fernandes, Elma
RA   Ashendel, Curtis L.
RA   Noda, Makoto
RA   Klein-Szanto, Andres J.P.
RT   "Partial suppression of tumorigenicity in a human lung cancer cell
RT   line transfected with Krev-1.";
RL   Mol. Carcinog. 6:252-259(1992).
//