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Cellosaurus NCC-GCTB9-C1 (CVCL_D4C1)

[Text version]
Cell line name NCC-GCTB9-C1
Accession CVCL_D4C1
Resource Identification Initiative To cite this cell line use: NCC-GCTB9-C1 (RRID:CVCL_D4C1)
Comments Part of: NCC sarcoma cell line panel.
Population: Japanese.
Characteristics: Can be grown as spheroids (PubMed=38466561).
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 12 hours (PubMed=38466561).
Derived from site: In situ; Bone, distal tibia; UBERON=UBERON_0004405.
Sequence variations
  • Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Gly35Trp (c.103G>T) (G34W); Zygosity=Heterozygous (PubMed=38466561).
Disease Malignancy in giant cell tumor of bone (NCIt: C4304)
Giant cell tumor of bone (ORDO: Orphanet_363976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 33Y
Category Cancer cell line
STR profile Source(s): PubMed=38466561

Markers:
AmelogeninX
CSF1PO11
D5S8189,13
D7S8208,11
D13S31712
D16S5399,12
D21S1132
TH017,8
TPOX8
vWA17,19

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Publications

PubMed=38466561; DOI=10.1007/s13577-024-01042-5
Adachi Y., Noguchi R., Yoshimatsu Y., Sin Y., Osaki J., Ono T., Iwata S., Akiyama T., Tsuchiya R., Toda Y., Ishihara S., Ogura K., Kobayashi E., Kojima N., Yoshida A., Yokoo H., Kawai A., Kondo T.
Establishment and characterization of two novel patient-derived cell lines from giant cell tumor of bone: NCC-GCTB8-C1 and NCC-GCTB9-C1.
Hum. Cell 37:874-885(2024)

Cross-references
Encyclopedic resources Wikidata; Q127382930
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3