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Cellosaurus NCC-GCTB8-C1 (CVCL_D4C0)

[Text version]
Cell line name NCC-GCTB8-C1
Accession CVCL_D4C0
Resource Identification Initiative To cite this cell line use: NCC-GCTB8-C1 (RRID:CVCL_D4C0)
Comments Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 26 hours (PubMed=38466561).
Derived from site: In situ; Bone, right proximal tibia; UBERON=UBERON_0008772.
Sequence variations
  • Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Gly35Trp (c.103G>T) (G34W); Zygosity=Heterozygous (PubMed=38466561).
Disease Malignancy in giant cell tumor of bone (NCIt: C4304)
Giant cell tumor of bone (ORDO: Orphanet_363976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 32Y
Category Cancer cell line
STR profile Source(s): PubMed=38466561

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81812
D7S82011
D13S31711,12
D16S5399,10
D21S1131,32.2
TH018,9
TPOX8,11
vWA14,17

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Publications

PubMed=38466561; DOI=10.1007/s13577-024-01042-5
Adachi Y., Noguchi R., Yoshimatsu Y., Sin Y., Osaki J., Ono T., Iwata S., Akiyama T., Tsuchiya R., Toda Y., Ishihara S., Ogura K., Kobayashi E., Kojima N., Yoshida A., Yokoo H., Kawai A., Kondo T.
Establishment and characterization of two novel patient-derived cell lines from giant cell tumor of bone: NCC-GCTB8-C1 and NCC-GCTB9-C1.
Hum. Cell 37:874-885(2024)

Cross-references
Encyclopedic resources Wikidata; Q127382929
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3