Cellosaurus cell line KOPN-70 (CVCL

Cross-references
Cell line name	KOPN-70
Synonyms	KOPN70
Accession	CVCL_D3ZW
Resource Identification Initiative	To cite this cell line use: KOPN-70 (RRID:CVCL_D3ZW)
Comments	Population: Japanese.
Sequence variations	Mutation; HGNC; HGNC:12766; NSD2; Simple; p.Ala384Thr (c.1150G>A); dbSNP=rs767422079; Zygosity=Heterozygous (PubMed=35124168).
Disease	Childhood B acute lymphoblastic leukemia (NCIt: C9140) Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	9Y
Category	Cancer cell line
Publications	PubMed=29786757; DOI=10.1007/s12185-018-2474-7 Tomoyasu C., Imamura T., Tomii T., Yano M., Asai D., Goto H., Shimada A., Sanada M., Iwamoto S., Takita J., Minegishi M., Inukai T., Sugita K., Hosoi H. Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes. Int. J. Hematol. 108:312-318(2018) PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068 Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T. Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia. J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)
Encyclopedic resources	Wikidata; Q127382568
Entry history
Entry creation	30-Jan-2024
Last entry update	19-Dec-2024
Version number	3