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Cellosaurus TCC-Y/sr (CVCL_D3Z5)

[Text version]
Cell line name TCC-Y/sr
Synonyms TCC-Y / sr
Accession CVCL_D3Z5
Resource Identification Initiative To cite this cell line use: TCC-Y/sr (RRID:CVCL_D3Z5)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Japanese National Institute of Bioscience and Human-Technology, Agency of Industrial Science and Technology; FERM BP-8531.
Population: Japanese.
Doubling time: 34 +- 4 hours (Patent=WO2004094628A1).
Selected for resistance to: ChEBI; CHEBI_45783; Imatinib (Gleevec; STI571).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
  • Mutation; HGNC; HGNC:76; ABL1; Simple; p.Thr315Ile (c.944C>T) (c.1001C>T); ClinVar=VCV000012624; Zygosity=Unspecified (Patent=WO2004094628A1).
Disease Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D3Z4 (TCC-Y)
Sex of cell Sex unspecified
Age at sampling Adult
Category Cancer cell line
Publications

Patent=WO2004094628A1
Sato Y., Nagao H.
Imanitib-resistant Philadelphia chromosome-positive human acute lymphocytic leukemic cell line and utilization thereof.
Patent number WO2004094628A1, 04-Nov-2004

Cross-references
Encyclopedic resources Wikidata; Q127384378
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3