ID   NCC-PMP2-C1
AC   CVCL_D3Z1
DR   Wikidata; Q127382935
RX   PubMed=38143259;
CC   Population: Japanese.
CC   Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
CC   Doubling time: ~97 hours (PubMed=38143259).
CC   Sequence variation: Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=38143259).
CC   Sequence variation: Gene deletion; HGNC; HGNC:11389; STK11; Zygosity=Homozygous (PubMed=38143259).
CC   Sequence variation: Mutation; HGNC; HGNC:427; ALK; Simple; p.Thr122Met (c.365C>T); ClinVar=VCV000538194; Zygosity=Unspecified (PubMed=38143259).
CC   Sequence variation: Mutation; HGNC; HGNC:18037; ARID2; Simple; p.Gln25Ter (c.73C>T); Zygosity=Unspecified (PubMed=38143259).
CC   Sequence variation: Mutation; HGNC; HGNC:10261; ROS1; Simple; p.Pro151Leu (c.452C>T); Zygosity=Unspecified (PubMed=38143259).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys141Trp (c.423C>G); ClinVar=VCV000376564; Zygosity=Unspecified (PubMed=38143259).
CC   Omics: SNP array analysis.
CC   Derived from site: Metastatic; Peritoneal cavity; UBERON=UBERON_0001179.
ST   Source(s): PubMed=38143259
ST   Amelogenin: X
ST   CSF1PO: 9,10,12
ST   D13S317: 8
ST   D16S539: 9,10
ST   D21S11: 31,32.2
ST   D5S818: 9,12
ST   D7S820: 10,11
ST   TH01: 9
ST   TPOX: 8,12
ST   vWA: 14,17
DI   NCIt; C203949; High grade mucinous carcinoma peritonei with signet ring cells
DI   ORDO; Orphanet_26790; Pseudomyxoma peritonei
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 4
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RX   PubMed=38143259; DOI=10.1007/s13577-023-01015-0;
RA   Noguchi R., Yoshimatsu Y., Sin Y., Ono T., Tsuchiya R., Yoshida H.,
RA   Kiyono T., Yonemura Y., Kondo T.;
RT   "Establishment and characterization of NCC-PMP2-C1: a novel
RT   patient-derived cell line of pseudomyxoma peritonei with signet ring
RT   cells.";
RL   Hum. Cell 37:511-522(2024).
//