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Cellosaurus iMPEC-5 (CVCL_D3JT)

[Text version]
Cell line name iMPEC-5
Synonyms immortal Mouse Prostate Epithelial Cell line-5
Accession CVCL_D3JT
Resource Identification Initiative To cite this cell line use: iMPEC-5 (RRID:CVCL_D3JT)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Sex of cell Male
Age at sampling 6W
Category Transformed cell line
Publications

PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4
Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E.
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.
Methods Enzymol. 446:77-106(2008)

PubMed=19737977; DOI=10.1158/1541-7786.MCR-09-0166; PMCID=PMC2855683
Bray K., Chen H.-Y., Karp C.M., May M., Ganesan S., Karantza-Wadsworth V., DiPaola R.S., White E.
Bcl-2 modulation to activate apoptosis in prostate cancer.
Mol. Cancer Res. 7:1487-1496(2009)

Cross-references
Encyclopedic resources Wikidata; Q127382375
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2