ID   iMPEC-3
AC   CVCL_D3JR
SY   immortal Mouse Prostate Epithelial Cell line-3
DR   Wikidata; Q127382373
RX   PubMed=18603117;
RX   PubMed=19737977;
CC   Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   6W
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 10-09-24; Version: 2
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RX   PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4;
RA   Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E.;
RT   "Immortalized mouse epithelial cell models to study the role of
RT   apoptosis in cancer.";
RL   Methods Enzymol. 446:77-106(2008).
//
RX   PubMed=19737977; DOI=10.1158/1541-7786.MCR-09-0166; PMCID=PMC2855683;
RA   Bray K., Chen H.-Y., Karp C.M., May M., Ganesan S.,
RA   Karantza-Wadsworth V., DiPaola R.S., White E.;
RT   "Bcl-2 modulation to activate apoptosis in prostate cancer.";
RL   Mol. Cancer Res. 7:1487-1496(2009).
//