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Cellosaurus iBMK Atg5+/- 5.4 (CVCL_D3IC)

[Text version]
Cell line name iBMK Atg5+/- 5.4
Synonyms Atg5+/- 5.4; immortalized Baby Mouse Kidney epithelial cell line Atg5+/- 5.4
Accession CVCL_D3IC
Resource Identification Initiative To cite this cell line use: iBMK Atg5+/- 5.4 (RRID:CVCL_D3IC)
Comments Knockout cell: Method=KO mouse; MGI; MGI:1277186; Atg5 (Note=1 of 2 alleles).
Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Originate from same individual CVCL_D3I9 ! iBMK Atg5+/- 5.1
CVCL_D3IA ! iBMK Atg5+/- 5.2
CVCL_D3IB ! iBMK Atg5+/- 5.3
Sex of cell Sex unspecified
Age at sampling <2D
Category Transformed cell line
Publications

PubMed=17510285; DOI=10.1101/gad.1545107; PMCID=PMC1877749
Mathew R., Kongara S., Beaudoin B., Karp C.M., Bray K., Degenhardt K., Chen G.-H., Jin S.-K., White E.
Autophagy suppresses tumor progression by limiting chromosomal instability.
Genes Dev. 21:1367-1381(2007)

PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4
Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E.
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.
Methods Enzymol. 446:77-106(2008)

Cross-references
Encyclopedic resources Wikidata; Q127382108
Entry history
Entry creation30-Jan-2024
Last entry update10-Apr-2025
Version number3