Cellosaurus cell line iBMK BLN-4-1 (CVCL

Cellosaurus iBMK BLN-4-1 (CVCL_D3HQ)

Cross-references
Cell line name	iBMK BLN-4-1
Synonyms	BLN-4-1; BLN4-1; BCLN4-1; immortalized Baby Mouse Kidney epithelial cell line BLN-4-1
Accession	CVCL_D3HQ
Resource Identification Initiative	To cite this cell line use: iBMK BLN-4-1 (RRID:CVCL_D3HQ)
Comments	Knockout cell: Method=KO mouse; MGI; MGI:1891828; Becn1 (Note=1 of 2 alleles). Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein. Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Originate from same individual	CVCL_D3HP ! iBMK BLN-34-3 CVCL_D3HV ! iBMK BLNB-1 CVCL_D3HW ! iBMK BLNB-4 CVCL_D3HX ! iBMK BLNB-12 CVCL_D3HY ! iBMK BLNB-13
Age at sampling	5D
Category	Transformed cell line
Publications	PubMed=16843265; DOI=10.1016/j.ccr.2006.06.001; PMCID=PMC2857533 Degenhardt K., Mathew R., Beaudoin B., Bray K., Anderson D., Chen G.-H., Mukherjee C., Shi Y.-F., Gelinas C., Fan Y.-J., Nelson D.A., Jin S.-K., White E. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 10:51-64(2006) PubMed=17510285; DOI=10.1101/gad.1545107; PMCID=PMC1877749 Mathew R., Kongara S., Beaudoin B., Karp C.M., Bray K., Degenhardt K., Chen G.-H., Jin S.-K., White E. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev. 21:1367-1381(2007) PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4 Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E. Immortalized mouse epithelial cell models to study the role of apoptosis in cancer. Methods Enzymol. 446:77-106(2008)
Encyclopedic resources	Wikidata; Q127382152
Entry history
Entry creation	30-Jan-2024
Last entry update	10-Sep-2024
Version number	2