ID   iBMK K3
AC   CVCL_D3FY
SY   K3; immortalized Baby Mouse Kidney epithelial cell line K3
DR   Wikidata; Q127382226
RX   PubMed=11836241;
RX   PubMed=12242152;
RX   PubMed=18603117;
CC   Knockout cell: Method=KO mouse; MGI; MGI:1097161; Bak1.
CC   Knockout cell: Method=KO mouse; MGI; MGI:99702; Bax (Note=1 of 2 alleles).
CC   Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
AG   5D
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 10-09-24; Version: 2
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RX   PubMed=11836241; DOI=10.1074/jbc.M109939200;
RA   Degenhardt K., Sundararajan R., Lindsten T., Thompson C.B., White E.;
RT   "Bax and Bak independently promote cytochrome C release from
RT   mitochondria.";
RL   J. Biol. Chem. 277:14127-14134(2002).
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RX   PubMed=12242152; DOI=10.1016/S1535-6108(02)00126-5;
RA   Degenhardt K., Chen G.-H., Lindsten T., White E.;
RT   "BAX and BAK mediate p53-independent suppression of tumorigenesis.";
RL   Cancer Cell 2:193-203(2002).
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RX   PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4;
RA   Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E.;
RT   "Immortalized mouse epithelial cell models to study the role of
RT   apoptosis in cancer.";
RL   Methods Enzymol. 446:77-106(2008).
//