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Cellosaurus iBMK K1 (CVCL_D3FW)

[Text version]
Cell line name iBMK K1
Synonyms K1; K1-3; immortalized Baby Mouse Kidney epithelial cell line K1
Accession CVCL_D3FW
Resource Identification Initiative To cite this cell line use: iBMK K1 (RRID:CVCL_D3FW)
Comments Knockout cell: Method=KO mouse; MGI; MGI:1097161; Bak1.
Knockout cell: Method=KO mouse; MGI; MGI:99702; Bax (Note=1 of 2 alleles).
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Age at sampling 5D
Category Transformed cell line
Publications

PubMed=11836241; DOI=10.1074/jbc.M109939200
Degenhardt K., Sundararajan R., Lindsten T., Thompson C.B., White E.
Bax and Bak independently promote cytochrome C release from mitochondria.
J. Biol. Chem. 277:14127-14134(2002)

PubMed=12242152; DOI=10.1016/S1535-6108(02)00126-5
Degenhardt K., Chen G.-H., Lindsten T., White E.
BAX and BAK mediate p53-independent suppression of tumorigenesis.
Cancer Cell 2:193-203(2002)

PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4
Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E.
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.
Methods Enzymol. 446:77-106(2008)

Cross-references
Encyclopedic resources Wikidata; Q127382222
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2