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Cellosaurus CI-huThyrEC-2 (CVCL_D3FQ)

[Text version]
Cell line name CI-huThyrEC-2
Synonyms huThyrEC-2; A1
Accession CVCL_D3FQ
Resource Identification Initiative To cite this cell line use: CI-huThyrEC-2 (RRID:CVCL_D3FQ)
Comments Population: Caucasian.
Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=35663474).
Doubling time: 28.7 hours (PubMed=35663474).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5109; HOXA9.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7545; MYB.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11195; SOX2.
Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
Genetic integration: Method=Transduction; Gene=MGI; MGI:99187; Zfp42.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Miscellaneous: Although only one catalog number exists (INS-CI-1017), InSCREENeX distributes the 4 different CI-huThyrEC cell lines.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Cell type: Follicular cell; CL=CL_0002258.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D3FP ! CI-huThyrEC-1
CVCL_D3FR ! CI-huThyrEC-3
CVCL_D3FS ! CI-huThyrEC-4
Sex of cell Male
Age at sampling 18Y
Category Transformed cell line
Web pages Provider; InSCREENeX; INS-CI-1017; https://www.inscreenex.de/product/huthyrec/
Publications

PubMed=35663474; DOI=10.1089/aivt.2020.0027; PMCID=PMC9157743
Hopperstad K., Truschel T., Wahlicht T., Stewart W., Eicher A., May T., Deisenroth C.
Characterization of novel human immortalized thyroid follicular epithelial cell lines.
Appl. In Vitro Toxicol. 7:39-49(2021)

Cross-references
Encyclopedic resources Wikidata; Q127380556
Entry history
Entry creation30-Jan-2024
Last entry update10-Apr-2025
Version number4