Cellosaurus logo
expasy logo

Cellosaurus T1 1Cr NKX2.1 Pt 1 (CVCL_D3C4)

[Text version]
Cell line name T1 1Cr NKX2.1 Pt 1
Synonyms T1; T1-1Cr4
Accession CVCL_D3C4
Resource Identification Initiative To cite this cell line use: T1 1Cr NKX2.1 Pt 1 (RRID:CVCL_D3C4)
Comments From: Boston University School of Medicine; Boston; USA.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:11825; NKX2-1; Simple; p.Pro129Glyfs (c.384_391delGCCGTACC); Zygosity=Unspecified (PubMed=26593959).
Disease Choreoathetosis, hypothyroidism, and neonatal respiratory distress (NCIt: C202546)
Brain-lung-thyroid syndrome (ORDO: Orphanet_209905)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 5Y
Category Induced pluripotent stem cell
Web pages https://stemcellbank.bu.edu/Catalog/Item/Details/590
Publications

PubMed=26593959; DOI=10.1016/j.stem.2015.09.004; PMCID=PMC4666682
Kurmann A.A., Serra M., Hawkins F., Rankin S.A., Mori M., Astapova I., Ullas S., Lin S., Bilodeau M., Rossant J., Jean J.-C., Ikonomou L., Deterding R.R., Shannon J.M., Zorn A.M., Hollenberg A.N., Kotton D.N.
Regeneration of thyroid function by transplantation of differentiated pluripotent stem cells.
Cell Stem Cell 17:527-542(2015)

Cross-references
Encyclopedic resources Wikidata; Q127384360
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3