| Cell line name |
NSC-34 |
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| Synonyms |
NSC 34; NSC34; Neuroblastoma x Spinal Cord-34 |
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| Accession |
CVCL_D356 |
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| Resource Identification Initiative |
To cite this cell line use: NSC-34 (RRID:CVCL_D356) |
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| Comments |
Characteristics: Produced by the fusion of motor neuron enriched, embryonic 12-14 days mouse spinal cord cells with N18TG2 (PubMed=1467557).
Omics: Deep proteome analysis.
Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma. |
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| Species of origin |
Mus musculus (Mouse)
(NCBI Taxonomy: 10090) |
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| Hierarchy |
Parent: CVCL_2132 (N18TG2)
Children:
|
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| Category |
Hybrid cell line |
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| STR profile |
Source(s): Direct_author_submission
Markers:| Mouse STR 1-1 | 11 |
| Mouse STR 1-2 | 17,18 |
| Mouse STR 2-1 | 9,16 |
| Mouse STR 3-2 | 13,14 |
| Mouse STR 4-2 | 19.3,22.3 |
| Mouse STR 5-5 | 14,15,17 |
| Mouse STR 6-4 | 18.3,19,20 |
| Mouse STR 6-7 | 12,15 |
| Mouse STR 7-1 | 25.2,26.2,30 |
| Mouse STR 8-1 | 16,17 |
| Mouse STR 11-2 | 15,16 |
| Mouse STR 12-1 | 16,17 |
| Mouse STR 13-1 | 16.2,17.2,18.2 |
| Mouse STR 15-3 | 22.3,23.3 |
| Mouse STR 17-2 | 15,16 |
| Mouse STR 18-3 | 22,23 |
| Mouse STR 19-2 | 12,13 |
| Mouse STR X-1 | 25,26,29 |
Run an STR similarity search on this cell line |
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| Web pages |
https://www.cedarlanelabs.com/Products/Detail/CLU140?lob=AllProducts |
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| Publications | PubMed=1467557; DOI=10.1002/aja.1001940306
Cashman N.R., Durham H.D., Blusztajn J.K., Oda K., Tabira T., Shaw I.T., Dahrouge S., Antel J.P.
Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons.
Dev. Dyn. 194:209-221(1992) PubMed=17896795; DOI=10.1002/jnr.21507
Matusica D., Fenech M.P., Rogers M.-L., Rush R.A.
Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking.
J. Neurosci. Res. 86:553-565(2008) PubMed=25193168; DOI=10.1074/mcp.M113.037291; PMCID=PMC4256493
Hornburg D., Drepper C., Butter F., Meissner F., Sendtner M., Mann M.
Deep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics.
Mol. Cell. Proteomics 13:3410-3420(2014) PubMed=27242431; DOI=10.3389/fncel.2016.00118; PMCID=PMC4860417
Madji Hounoum B., Vourc'h P., Felix R., Corcia P., Patin F., Gueguinou M., Potier-Cartereau M., Vandier C., Raoul C., Andres C.R., Mavel S., Blasco H.
NSC-34 motor neuron-like cells are unsuitable as experimental model for glutamate-mediated excitotoxicity.
Front. Cell. Neurosci. 10:118.1-118.12(2016) |
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| Cross-references |
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| Cell line databases/resources |
Lonza; 5
|
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| Anatomy/cell type resources |
BTO; BTO:0004488
|
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| Encyclopedic resources |
Wikidata; Q54931057
|
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| Entry history |
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| Entry creation | 22-Oct-2012 |
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| Last entry update | 10-Sep-2024 |
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| Version number | 12 |
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