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Cellosaurus Lec1/hPDPN (CVCL_D2U0)

[Text version]
Cell line name Lec1/hPDPN
Accession CVCL_D2U0
Resource Identification Initiative To cite this cell line use: Lec1/hPDPN (RRID:CVCL_D2U0)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:29602; PDPN.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; Q924C0; Mgat1; Simple; p.Gln339Arg; Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; Q924C0; Mgat1; Simple; p.Lys401Arg; Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_3440 (Lec1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=25080943; DOI=10.1038/srep05924; PMCID=PMC4118152
Kato Y., Kaneko M.K.
A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin.
Sci. Rep. 4:5924-5924(2014)

PubMed=26937552; DOI=10.1089/mab.2015.0077
Kato Y., Ogasawara S., Oki H., Honma R., Takagi M., Fujii Y., Nakamura T., Saidoh N., Kanno H., Umetsu M., Kamata S., Kubo H., Yamada M., Sawa Y., Morita K.-i., Harada H., Suzuki H., Kaneko M.K.
Novel monoclonal antibody LpMab-17 developed by CasMab technology distinguishes human podoplanin from monkey podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 35:109-116(2016)

PubMed=27328060; DOI=10.1089/mab.2016.0006
Ogasawara S., Kaneko M.K., Honma R., Oki H., Fujii Y., Takagi M., Suzuki H., Kato Y.
Establishment of mouse monoclonal antibody LpMab-13 against human podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 35:155-162(2016)

Patent=US10227407
Kato Y., Kaneko M.K.
Anti-podoplanin antibody.
Patent number US10227407, 12-Mar-2019

Cross-references
Encyclopedic resources Wikidata; Q127382585
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3