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Cellosaurus PDIS-13 (CVCL_D2TP)

[Text version]
Cell line name PDIS-13
Synonyms LN229/hPODXL-knockout
Accession CVCL_D2TP
Resource Identification Initiative To cite this cell line use: PDIS-13 (RRID:CVCL_D2TP)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 9171; PODXL.
Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
Sequence variations
  • Mutation; HGNC; 6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0393 (LN-229)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=28384052; DOI=10.1089/mab.2017.0008; PMCID=PMC5404275
Ogasawara S., Kaneko M.K., Yamada S., Honma R., Nakamura T., Saidoh N., Yanaka M., Yoshida K., Fujii Y., Kato Y.
PcMab-47: novel antihuman podocalyxin monoclonal antibody for immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother. 36:50-56(2017)

Cross-references
Encyclopedic resources Wikidata; Q127383035
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2