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Cellosaurus LN229/CD19ec (CVCL_D2TI)

[Text version]
Cell line name LN229/CD19ec
Accession CVCL_D2TI
Resource Identification Initiative To cite this cell line use: LN229/CD19ec (RRID:CVCL_D2TI)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1633; CD19 (Note=Extracellular domain, with a N-terminal GVAMPGAEDDVV = PA-tag and a C-terminal DMVNPGLEDRIE = RAP-tag and GDGMVPPGIEDK = MAP-tag).
Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
Sequence variations
  • Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0393 (LN-229)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=32271687; DOI=10.1089/mab.2020.0003
Yamada S., Kaneko M.K., Sayama Y., Asano T., Sano M., Yanaka M., Nakamura T., Okamoto S., Handa S., Komatsu Y., Nakamura Y., Furusawa Y., Takei J., Kato Y.
Development of novel mouse monoclonal antibodies against human CD19.
Monoclon. Antib. Immunodiagn. Immunother. 39:45-50(2020)

Cross-references
Encyclopedic resources Wikidata; Q127382602
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3