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Cellosaurus LN229/mEGFR (CVCL_D2SJ)

[Text version]
Cell line name LN229/mEGFR
Accession CVCL_D2SJ
Resource Identification Initiative To cite this cell line use: LN229/mEGFR (RRID:CVCL_D2SJ)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:95294; Egfr (Note=With a N-terminal GVAMPGAEDDVV = PA-tag).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
Sequence variations
  • Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0393 (LN-229)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=37489364; DOI=10.3390/antib12030042; PMCID=PMC10366908
Goto N., Suzuki H., Tanaka T., Ishikawa K., Ouchida T., Kaneko M.K., Kato Y.
EMab-300 detects mouse epidermal growth factor receptor-expressing cancer cell lines in flow cytometry.
Antibodies (Basel) 12:42.1-42.11(2023)

Cross-references
Encyclopedic resources Wikidata; Q127382610
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3