Cellosaurus HEK293::TMEM192-3xHA YIPF4-/-;YIPF3-/- (CVCL_D1J4)
Cell line name | HEK293::TMEM192-3xHA YIPF4-/-;YIPF3-/- |
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Synonyms | YIPF3/YIPF4-/- DKO HEK293; HEK293 YIPF3-/-;YIPF4-/- |
Accession | CVCL_D1J4 |
Resource Identification Initiative | To cite this cell line use: HEK293::TMEM192-3xHA YIPF4-/-;YIPF3-/- (RRID:CVCL_D1J4) |
Comments | Characteristics: Using CRISPR/Cas9 TMEM192 was C-terminally tagged on both alleles with a 3xHA epitope (from parent cell line). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:21023; YIPF3. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28145; YIPF4. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_D1J3 (HEK293::TMEM192-3xHA YIPF4-/-) |
Sex of cell | Female |
Age at sampling | Fetus |
Category | Transformed cell line |
Publications | PubMed=37757899; DOI=10.1038/s41586-023-06657-6; PMCID=PMC10620096 |
Cross-references | |
Encyclopedic resources | Wikidata; Q127381652 |
Entry history | |
Entry creation | 30-Jan-2024 |
Last entry update | 19-Dec-2024 |
Version number | 4 |