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Cellosaurus HEK293T D9 T antigen and neo deletion clone #12 (CVCL_D1HN)

[Text version]
Cell line name HEK293T D9 T antigen and neo deletion clone #12
Accession CVCL_D1HN
Resource Identification Initiative To cite this cell line use: HEK293T D9 T antigen and neo deletion clone #12 (RRID:CVCL_D1HN)
Comments Characteristics: Using CRISPR/Cas9 the SV40 large and small T-antigen coding sequences were deleted as well as the neo resistance gene (PubMed=32775497).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D1HM (HEK293T D9)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=32775497; DOI=10.1016/j.omtm.2020.07.006; PMCID=PMC7397404
Bae D.H., Marino M., Iaffaldano B., Fenstermaker S., Afione S.A., Argaw T., McCright J., Kwilas A., Chiorini J.A., Timmons A.E., Reiser J.
Design and testing of vector-producing HEK293T cells bearing a genomic deletion of the SV40 T antigen coding region.
Mol. Ther. Methods Clin. Dev. 18:631-638(2020)

Cross-references
Encyclopedic resources Wikidata; Q127381672
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2