Cellosaurus cell line MGG6 (CVCL

Cellosaurus MGG6 (CVCL_D1H2)

Cross-references
Cell line name	MGG6
Accession	CVCL_D1H2
Resource Identification Initiative	To cite this cell line use: MGG6 (RRID:CVCL_D1H2)
Comments	Group: Cancer stem cell line. Omics: Array-based CGH. Omics: H3K27ac ChIP-seq epigenome analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=22067563). Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (PubMed=22067563).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=22067563; DOI=10.1093/neuonc/nor195; PMCID=PMC3266381 Wakimoto H., Mohapatra G., Kanai R., Curry W.T. Jr., Yip S., Nitta M., Patel A.P., Barnard Z.R., Stemmer-Rachamimov A.O., Louis D.N., Martuza R.L., Rabkin S.D. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro-oncol. 14:132-144(2012) PubMed=24726434; DOI=10.1016/j.cell.2014.02.030; PMCID=PMC4004670 Suva M.L., Rheinbay E., Gillespie S.M., Patel A.P., Wakimoto H., Rabkin S.D., Riggi N., Chi A.S., Cahill D.P., Nahed B.V., Curry W.T. Jr., Martuza R.L., Rivera M.N., Rossetti N., Kasif S., Beik S., Kadri S., Tirosh I., Wortman I., Shalek A.K., Rozenblatt-Rosen O., Regev A., Louis D.N., Bernstein B.E. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell 157:580-594(2014)
Encyclopedic resources	Wikidata; Q127382823
Gene expression databases	GEO; GSM1306340 GEO; GSM1306343 GEO; GSM1324078 GEO; GSM1324079 GEO; GSM1324080 GEO; GSM1324087 GEO; GSM1324088 GEO; GSM1324089
Entry history
Entry creation	30-Jan-2024
Last entry update	19-Dec-2024
Version number	3