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Cellosaurus MGG6 (CVCL_D1H2)

[Text version]
Cell line name MGG6
Accession CVCL_D1H2
Resource Identification Initiative To cite this cell line use: MGG6 (RRID:CVCL_D1H2)
Comments Group: Cancer stem cell line.
Omics: Array-based CGH.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=22067563).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (PubMed=22067563).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=22067563; DOI=10.1093/neuonc/nor195
Wakimoto H., Mohapatra G., Kanai R., Curry W.T. Jr., Yip S., Nitta M., Patel A.P., Barnard Z.R., Stemmer-Rachamimov A.O., Louis D.N., Martuza R.L., Rabkin S.D.
Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.
Neuro-oncol. 14:132-144(2012)

PubMed=24726434; DOI=10.1016/j.cell.2014.02.030
Suva M.L., Rheinbay E., Gillespie S.M., Patel A.P., Wakimoto H., Rabkin S.D., Riggi N., Chi A.S., Cahill D.P., Nahed B.V., Curry W.T. Jr., Martuza R.L., Rivera M.N., Rossetti N., Kasif S., Beik S., Kadri S., Tirosh I., Wortman I., Shalek A.K., Rozenblatt-Rosen O., Regev A., Louis D.N., Bernstein B.E.
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells.
Cell 157:580-594(2014)

Cross-references
Gene expression databases GEO; GSM1306340
GEO; GSM1306343
GEO; GSM1324078
GEO; GSM1324079
GEO; GSM1324080
GEO; GSM1324087
GEO; GSM1324088
GEO; GSM1324089
Entry history
Entry creation30-Jan-2024
Last entry update30-Jan-2024
Version number1