Cellosaurus hIPSC-Di21-C3-1-2 (CVCL_D1FF)
| Cell line name | hIPSC-Di21-C3-1-2 |
|---|---|
| Synonyms | Di C3-1-2; C3-1-2 |
| Accession | CVCL_D1FF |
| Resource Identification Initiative | To cite this cell line use: hIPSC-Di21-C3-1-2 (RRID:CVCL_D1FF) |
| Comments | Population: Caucasian. Characteristics: Using CRISPR/Cas9 a IRES-TK-Neo-polyA site cassette was introduced in one allele of exon 3 of APP on chromosome 21 (PubMed=23084023). Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK. Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Chest, skin; UBERON=UBERON_0001868. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Disease | Down syndrome (NCIt: C2993) Down syndrome (ORDO: Orphanet_870) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_D1FA (hIPSC-Tri21-C3-1) |
| Sex of cell | Female |
| Age at sampling | 1Y |
| Category | Induced pluripotent stem cell |
| Publications | PubMed=23084023; DOI=10.1016/j.stem.2012.08.004; PMCID=PMC3705773 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q127381762 |
| Entry history | |
| Entry creation | 30-Jan-2024 |
| Last entry update | 10-Sep-2024 |
| Version number | 2 |